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MegaNatural® Grape Seed and Skin Extracts

MegaNatural® Grape Seed and Skin Extracts

  • Dry & Liquid Forms
  • MegaNatural® BP
    Grape Seed Extract, patent pending cardiac health claims suitable for liquid and solid dosage
    Grape Seed Extract, patent-pending to help maintain healthy blood glucose levels within the normal range suitable for solid dosage
    MegaNatural® Gold
    Grape Seed Extract, NLT 90% total phenols, suitable for liquid or solid dosage
    MegaNatural® GSKE
    Grape Pomace (skin) Extract, NLT 80% phenols, for liquid or solid dosage
    MegaNatural® GSKE 40
    Grape Pomace (skin) Extract, NLT 40% phenols, suitable for liquid or solid dosage
    Nutraceutical Grade
    Grape Pomace (skin) Extract, NLT 25% phenols, suitable for liquid or solid dosage
    MegaNatural® Rubired
    Whole Grape Extract, suitable for beverages, bars, solid dosage

MegaNatural BP and MegaNatural Gold


Nitric Oxide and MegaNatural BP


Lowering Blood Pressure with MegaNatural BP

MegaNatural® Downloads

Polyphenolic Blog

  • Health and nutrition professionals across the U.S. are reading about MegaNatural-GL, the newest member of the Polyphenolics family of ingredients, which is designed to help consumers manage blood sugar spikes and oxidative stress. writer Hank Schultz researched and wrote … Continue reading →The post Major trade publication’s feature article helps Polyphenolics launch its sports nutrition ingredient appeared first on Polyphenolics.

  • Dr. Britt Burton-Freeman Ph.D., M.S., Director of Nutrition, for the Center for Nutrition Research at the Institute for Food Safety and Health at the Illinois Institute for Technology Interview reveals the latest research and advancements on pre-hypertension With an estimated … Continue reading →The post Dr. Britt Burton-Freeman discusses significance of MegaNatural-BP research appeared first on Polyphenolics.

  • Promising results of human clinical studies using MegaNatural-BP were reported in the October 2013 print and online issues of the Journal of Food Science, an Institute of Food Technologists publication that is read by members of the food science community … Continue reading →The post MegaNatural-BP research featured in prestigious international publication appeared first on Polyphenolics.

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  • Grape Seed Extract for Blood Pressure? Study: Grape Seed Extract May Help Tame Prehypertension By Miranda Hitti WebMD Health News Reviewed by Louise Chang, MD Grape seed extract might help control blood pressure, a new study shows. The news comes from scientists at the University of California at Davis. They studied 24 adults with metabolic syndrome, a cluster of abnormalities that raises the risk of diabetes and heart disease. Most participants had prehypertension; the others had normal blood pressure. Prehypertension falls between normal and high blood pressure. Participants were split into three groups. One group got a fake (placebo) treatment. Another group took 150 milligrams per day of grape seed extract. The third group took 300 milligrams daily of the same grape seed extract. Four weeks later, blood pressure had dropped for those taking grape seed extract. Blood pressure didn't change in the placebo group. The findings were presented in Atlanta at the American Chemical Society's National Meeting & Exposition. Blood Pressure Effects The two extract doses were "equally efficient in lowering the blood pressure," researcher C. Tissa Kappagoda, MD, PhD, tells WebMD. Kappagoda specializes in cardiovascular medicine at the University of California at Davis. Systolic blood pressure (the top number in a blood pressure reading) dropped 12 points, on average. Diastolic blood pressure (the bottom number in a blood pressure reading) dropped an average of 8 points, Kappagoda says. The blood pressure changes were seen "across the board," not just in people with prehypertension, says Kappagoda. He notes that his team had already done preliminary work on people with normal blood pressure and found no dangerous drop in blood pressure with grape seed extract. Kappagoda and colleagues had previously found that grape seed extract might help dilate blood vessels. "Because of that, we thought it had potential as a blood-pressure-lowering agent," Kappagoda says. In Kappagoda's latest study, LDL "bad" cholesterol levels also fell in people taking the higher extract dose, but not in those taking the lower dose. Talk to Doctor First Grape seed extract isn't marketed with any health claims, Kappagoda points out. He says people who are thinking about taking grape seed extract should consult their doctors. Kappagoda also says he "wouldn't want to recommend" that anyone stop taking medicine for high blood pressure in favor of grape seed extract. "But on the other hand, if their physicians have said, 'You know, you're kind of borderline,' and so on, then there may be some place for this after consulting their physician," Kappagoda says, pointing out that doctors usually recommend lifestyle change -- not prescription drugs -- to treat prehypertension. The study was funded by the extract's maker, Polyphenolics Inc.

    Sunday, 26 April 2015


    Thursday, 23 April 2015

  • All Grape seed Extracts Are Not Created Equal! Don't Cut Corners With Inferior Quality Grape Seed Extract For Your Formulations And Look For MegaNatural Logo In Your Products, Polyphenolics Produces a Powerful Anti-Oxidant and is the Only Proven Choice For Your GSE Needs:

    Thursday, 26 March 2015

  • As a division of Constellation Brands, Polyphenolics has access to an abundant supply of quality U.S.-grown grapes and retains complete control over the entire manufacturing process, from the initial selection of wine grapes to the final extraction of finished material. Dedication to Science Polyphenolics has invested considerable resources into identifying the particular molecular structures within grape seed that provide the greatest health benefits. In addition, Polyphenolics relentlessly tests its products for: Efficacy, through human clinical trials Mechanism of action, through laboratory research Consistency, through HPLC testing Safety, through microbiological, pesticide and heavy metal testing - See more at:

    Tuesday, 10 March 2015

  • MegaNatural®-BP is a distinct form of grape seed extract in that it is backed by human clinical research, which is rare in the industry. It is also supported by a portfolio of intellectual property, including a trademarked brand name and manufacturing and usage patents, further differentiating it from other commodity grape seed extracts. The ingredient fills a need for a natural, effective solution to common health concerns, such as high blood pressure, and is attractive to those seeking a solution without the side effects associated with pharmaceutical drugs. MegaNatural®-BP has achieved FDA No-Objection GRAS status, making it safe to add to existing brands or new product launch. - See more at:

    Tuesday, 10 March 2015